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Over a thousand anti-cop activists tried to shut down Fifth Avenue in Midtown and the Upper East Side on Tuesday– defying Mayor Bill de Blasio‘s call for a moratorium on the demonstrations after two Brooklyn police officers were slain.

Many of the activists took shots at the mayor.

“The mayor says stop that, we say fuck that!” yelled activists, while jumping in place. The group started on 59th Street and 5th Avenue, went down to 53rd Street, and then marched up the Upper East Side.

Activists said they planned to march up to East Harlem, and then protest at a local precinct.

Tarik Grand, 25, of Brooklyn said he was out there because of de Blasio’s words on Monday. “We’re protesting tonight, because the mayor specifically said not to,” he said. “They asked for a moment of silence for the cops, but not for Garner.”

Most of the agitators chanted angrily at the police. “How do you spell murderers? N-Y-P-D!” said the agitators.

“NYPD, KKK, how many kids did you kill today?” other protesters chanted, who started on the sidewalk before moving onto the streets of Fifth and Madison Avenue.

The activists choked the traffic– and left an ambulance from New York Presbyterian stranded on 54th Street and 5th Avenue.

They moving downtown on 5th Avenue from 59th Street about 5:30 p.m. The demonstration has been organized by the Act Now To End War & Stop Racism Coalition, which has blasted de Blasio’s words as an effort to “chill the expression of free speech rights.”

The activists are using the hashtags “jailkillercops” and “winter of resistance” to organize their activities.

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Two heroic Brooklyn police officers were executed Saturday– after weeks of protests following a grand jury’s decision not to indict a cop who fatally choked Staten Island man Eric Garner while taking him into police custody.

“Personally, I feel it was horrible what happened to the police officers,” said Frangy Pozo, 21, a student at Rutger’s University. “We’re not saying we’re against them. [But] just because they died shouldn’t slow us down.”