At least two people were fatally shot in Lower Manhattan Tuesday afternoon by a gunman firing from his truck, police sources said.

The gunman, who is in police custody, shot at least six people at West Street and Chambers Street, which is near Stuyvesant High School, at 3:15 p.m.

“What happened was there was a car crash… he came out of one of the cars. He had two guns. He was running around Chambers and somebody started to chase him,” said a 14-year-old Stuyvesant student. “I heard four to six gunshots – everybody starts running.”

Video of the scene shows at least two people lying limp in the street. Photos show a smashed up Home Depot rental truck.

Police shut down the FDR to rush victims to Bellevue Hospital.

At least two people were fatally shot in Lower Manhattan Tuesday afternoon by a gunman firing from his truck, police sources said.

The gunman, who is in police custody, shot at least six people at West Street and Chambers Street, which is near Stuyvesant High School, at 3:15 p.m.

“What happened was there was a car crash… he came out of one of the cars. He had two guns. He was running around Chambers and somebody started to chase him,” said a 14-year-old Stuyvesant student. “I heard four to six gunshots – everybody starts running.”

Video of the scene shows at least two people lying limp in the street. Photos show a smashed up Home Depot rental truck.

Police shut down the FDR to rush victims to Bellevue Hospital.

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