Bigger creatures should have more cancer risk. However, Elephants do not have high rates of cancer. They have some kind of protection.
* elephants have 20 extra duplicates of p53, a tumor suppressor gene.
* they also duplicate copies of the LIF gene, which encodes for leukemia inhibitory factor.
Elephant cells commit suicide at the first hint of abnormality.
Above – Lucy Reading-Ikkanda/Quanta Magazine