Source:  Anna Rodgers

(By Dr. Cass Ingram, D.O.) What an impressive finding it is and highly newsworthy. It is mentioned throughout the news the issue of “cytokine storm” and the danger this poses to people. Yet, incredibly, a mere wild plant and its essential oil are medicinal beyond all drugs, in fact, a litany of them. Wild oregano is a powerhouse for reducing inflammation in the tissues. In a number of studies it has been found to inhibit the source of this condition primarily through its actions on inflammatory markers. Actually, the mechanism is truly profound, because wild oregano acts on the genes that lead to the synthesis of these markers. Repeatedly, it has been shown, oregano oil and its active components, including carvacrol and thymol, have demonstrated great powers against inflammation. In fact, in some studies oregano oil active ingredients were able to drop COX-2 inflammation levels by up to 80%.

Today, there is much concern about the inflammation that results from overwork of the immune system or might it be said, overreactions. In a study on T lymphocytes done via cell culture it was found that the wild oregano oil active ingredients exhibited a specific molecular action even more potent than drugs. Carvacrol and thymol both significantly reduced tissue levels of interleukin-2. In fact, the reduction was massive, two-thirds in the case of carvacrol. This makes it more significant in this regard than any drug. For gamma interferon, the reduction was nearly 30%. This proved that the oregano oil component modified the activity, that is more towards normal, during a crisis event. Correlating this to humans aggressive dosing would likely reduce this further.

In the lungs oregano oil has been found to curb reactive oxygen species or free radicals. This has led to in asthmatic patients a reduction in cytokine overload. Here, it largely shuts off the gene responsible for the immunological storm reaction. Whether in the lungs or the skin—or the rest of the organs—cytokines are no match for the powers of wild oregano.

In another investigation the oil was found to decrease inflammation in skin tissue, once again an action thought to be due to modulating immune function. Specifically, the oil was found to markedly act with actions to block excessive cell growth, known as anti proliferative activity, while also greatly inhibited markers of inflammation. These markers included various cytokines and also gamma interferon. In fact, through the powers of this oil nearly all elements associated with toxic inflammation are greatly reduced, including various collagen-associated molecules, cancer-inducing growth factors, and enzymes—the ones that can do us harm.  “Strongly inhibited” were among the comments made by investigators. As well, it was found to decisively block those specialized genes directly associated with inflammation. This caused them to conclude that oregano oil is a “promising candidate for use” against inflammation and cancerous changes in skin tissues.

Also, to reiterate, according to Iranian investigators oregano compounds were found to reduce all the serious immune modulators. This was through a direct action on the genes. This led to a reduction in the excessive activity of T cells. The various inflammatory cytokines were significantly reduced,  including the highly noxious tumor necrosis factor alpha. This led the researchers to stated that oregano oil would be useful to combat diseases associated with over-activity of immunity.

Wild oregano is far from specific to the skin. It helps reduce inflammation all throughout the body, including within all internal organs. Nothing is an exception to its powers. Consider an investigation in artificially induced colitis in animals. Treatment of the colitis condition with oregano oil decreased levels of all pro-inflammatory cytokines, including tumor necrosis factor alpha. A moderate dosage of oregano oil, only 1 per 1000, was sufficient to reduce all the key interleukin-based inflammation-promoters. The result was decreased mortality rate, combined with a better weight gain and reduced visible damage to colonic tissue. By influencing the genes, that is the production of the messenger form of RNA, it was concluded, oregano reverses the colitis pathology, a most significant finding.