JAMA study points to a higher likelihood of developing Bell’s palsy following COVID-19 vaccination compared to placebo
Posted BY: | NwoReport
People who received COVID-19 vaccinations were more likely to develop Bell’s palsy than those given a placebo, according to a review of multiple studies.
The review, published in the JAMA Network journal on April 27, looked at whether rates of Bell’s palsy were different between those who received a COVID-19 vaccination and those who were given a placebo.
Bell’s palsy is a temporary paralysis or weakness on one side of the face, with the condition usually improving after a few weeks. The condition has been reported as an adverse event following COVID-19 vaccination. However, a causative relationship between the two has so far not been established. For the review, the researchers analyzed 50 studies.
In phase 3 trials of all four major vaccines that were approved and administered globally, the incidence of Bell’s palsy was found to be “significantly higher” in the vaccinated group compared to a placebo group, according to the review. The vaccines were manufactured by Pfizer, Moderna, Johnson & Johnson, and AstraZeneca.
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A placebo is a treatment that does not contain any active ingredients, and participants in the test did not know whether they received a vaccine or a placebo.
“For the mRNA vaccine subgroup, there were significantly increased odds of Bell’s palsy in the vaccinated group compared with the placebo group … However, for the viral vector vaccine subgroup, the analysis yielded insignificant results,” the review said.
“This systematic review and meta-analysis suggests a higher incidence of Bell’s palsy among SARS-CoV-2–vaccinated vs placebo groups.”